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Human CellExp KLF4-TAT, Human Recombinant

A transcription factor that act both as an activator and as a repressor.
Catalog #: P1011
SKU-Size Size Price Qty
P1011-20 20 μg
$165.00
P1011-100 100 μg
$685.00
More Sizes Get Quote

Product Details

Alternate Name Krueppel-like factor 4, Epithelial zinc finger protein EZF, Gut-enriched krueppel-like factor, EZF, GKLF
Gene Symbol KLF4
Gene ID 9314
Accession # O43474
Source HEK293 cells
Appearance Dry powder
Physical Form Description Lyophilized powder
Molecular Weight 51.7 kDa
Purity by SDS-PAGE >90%
Purity by ≥90%
Endotoxin Level < 1 EU/μg
Reconstitution Instructions Reconstitute in sterile deionized water to a concentration of 0.1-1.0 mg/ml. Do not vortex. Additional carrier protein (example 0.1% BSA) is recommended for long term storage.
Amino Acid Sequence Isoform 2 of Krueppel-like factor 4 with 13-residue C-terminal TAT peptide (GGYGRKKRRQRRR)
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.


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