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Human Carcinoembryonic Antigen

Potential oncogene that modulates cell adhesion; native protein isolated from human liver metastases
Catalog #: P1712
$325.00

Product Details

Cat # +Size P1712-100
Size 100 µg
Alternate Name CEA Cell Adhesion Molecule 5; Carcinoembryonic antigen-related cell adhesion molecule 5; Meconium antigen 100; CD66e; CEA; carcinoembryonic antigen; CD66e antigen; CEACAM5
Gene ID 1048
Accession # P06731
Source Human liver metastases
Appearance Lyophilized protein
Physical Form Description Lyophilized powder
Molecular Weight 77 kDa predicted; 180 kDa observed (due to extensive glycosylation)
Purity by SDS-PAGE ≥ 95%
Biological Activity Activity verified by Accubind ELISA
Reconstitution Instructions Reconstitute using neutral pH buffer of choice
Amino Acid Sequence Full length native protein
Handling Centrifuge the vial prior to opening.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The carcinoembryonic antigen (CEA) protein is a cell surface glycoprotein. CEA plays a role as an oncogene by promoting tumor progression through its modulation of cell adhesion and intracellular signaling, and inducing resistance to anoikis of colorectal carcinoma cells. CEA is therefore useful as a clinical biomarker for gastrointestinal cancers.


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