Product Details
| Alternate Name | SNCA; Non-A beta component of AD amyloid; NACP; PARK1; PARK4; Non-A4 component of amyloid precursor; PD1 |
|---|---|
| Accession # | P37840, NP_000336 |
| Source | E.coli |
| Appearance | Liquid |
| Molecular Weight | 14.4 kDa |
| Purity by SDS-PAGE | ≥ 95% |
| Endotoxin Level | < 1 EU/μg of protein as determined by LAL method |
| Amino Acid Sequence | aa 1-140 |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -20ºC |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Alpha-Synuclein is a neuronal protein that plays an important role in presynaptic signaling and membrane trafficking. It is a soluble, natively unfolded protein with an extended structure primarily composed of random coils. It aggregates and interacts with other proteins such as synphilin-1, to induce neuronal cell toxicity in Parkinson's disease.
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