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HSV-1 IgM ELISA Kit

A Sandwich ELISA kit for the qualitative detect HSV-1 IgM in human serum or plasma.
Catalog #: E4681
$450.00

Product Details

Cat # +Size E4681-100
Size 96 assays
Kit Summary • Detection method- Absorbance (450 nm)
• Species reactivity- Human
• Application- quantitative measurement of HSV-1 IgM in serum and plasma.
Detection Method Absorbance (450 nm)
Species Reactivity Human
Applications This ELISA kit is used for quantitative measurement of HSV-1 IgM in serum and plasma.
Features & Benefits • Easy, convenient and time-saving method to measure the level of HSV-1 IgM in serum and plasma.
• No significant cross-reactivity or interference was observed.
Kit Components • Microplate
• Sample Diluent
• Calibrator
• Positive Control
• Negative Control
• Enzyme conjugate
• TMB Substrate
• Stop Solution
• Wash Buffer (20X)
Storage Conditions 4°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

HSV-1 and 2 are virtually identical, sharing approximately 50% of their DNA and have over 80% of common antigens. Both types infect the body's mucosal surfaces, usually the mouth or genitals, and then establish latency in the nervous system. For both types, at least two-thirds of infected people have no symptoms, or symptoms too mild to notice. However, both types can recur and spread even when no symptoms are present. By the time they're teenagers or young adults, about 50% of Americans have HSV-1 antibodies in their blood. By the time they are over age 50, some 80-90% of Americans has HSV-1 antibodies. By comparison, almost all HSV-2 is encountered after childhood, when people become sexually active. HSV type 1 is the cause of most orofacial herpes and HSV encephalitis; type 2 is the primary cause of initial and recurrent genital herpes and neonatal HSV. Reactivation of latent HSV infection is a frequent complication of immunosuppression due to cancer, transplantation and AIDS. Asymptomatic genital shedding of HSV-2 is more common than HSV-1 and occurs more frequently during the first 3 months after acquisition of primary type 2 disease than during later periods. The presence of HSV IgG antibody is indicative of previous exposure A significant increases in HSV IgG is an indicative of reactivation, current or recent infection. IgM antibody is present after primary HSV infection.


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