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Hsp90 Antibody

Catalog #: 3389
SKU-Size Size Price Qty
3389-30T 30 µg
$89.00
3389-100 100 µg
$280.00
More Sizes Get Quote

Product Details

Antibody Target Hsp90
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide surrounding amino acid 714 of human Hsp90
Accession # P07900
Gene ID 3320
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification Affinity purified
Species Reactivity Human, mouse, rat
Application Western blotting, Immunoprecipitation, Immunohistochemistry
Application & Usage Western blotting (0.5-4 µg/ml), in immunoprecipitation (10-20 µg/ml) and Immunohistochemistry (frozen sections, 10-20 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes Hsp90α and Hsp90β of human, mouse,
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Heat shock proteins (HSPs) are ubiquitously expressed in all organisms. A major function of HSP90 and other HSPs is to act as molecular chaperones. HSP90 forms a complex with glucocorticoid receptor (GR), rendering the non ligand-bound receptor transcriptionally inactive. HSP 90 binds the GR as a heterocomplex composed of either HSP56 or cyclophilin-40, forming an aporeceptor complex. HSP90 also exists as a dimer with other proteins such as p60/sti1 and p23, forming an aporeceptor complex with estrogen and androgen receptors.


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