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Hsp47 Antibody

based on 1 citations in multiple journalsHsp47 Antibody14.1 4
Catalog #: 3496
SKU-Size Size Price Qty
3496-30T 30 µg
$89.00
3496-100 100 µg
$265.00
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Product Details

Antibody Target Hsp47
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide surrounding amino acid 407 of human HSP47
Accession # P19324
Gene ID 12406
Appearance Colorless liquid
Concentration 0.2 mg/ml
Formulation 100 µg (0.2 mg/ml) Protein A purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification Affinity purified
Species Reactivity Human, mouse, rat, chicken
Application Western blot, Immunoprecipitation, Immunohistochemistry
Application & Usage Western blotting (0.5-4 µg/ml), immunoprecipitation (10-20 µg/ml) and Immunohistochemistry (10-20 µg/ml) in frozen or paraffin embedded tissues. However, the optimal concentrations should be determined individually. The antibody recognizes 47 kDa Hsp47 of
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Heat shock proteins (HSPs) are ubiquitously expressed in all organisms. HSP47 is a molecule expressed constitutively in cells that synthesizes collagen. HSP47 is a procollagen-specific molecular chaperon that resides in the endoplasmic reticulum of procollagen-producing cells and is essential for secretion of procollagen from cells. Significantly, HSP47 plays a vital role in folding and assembling collagen. HSP47 is also known as colligin 1, serpinh1, collagen-binding protein 1 (CBP1) and gp46. The human HSP 47 gene encodes a 47 kDa protein.


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Cheng S. et al. (2006) FASEB J. 20: 1898-1900.
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