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Hsc70 Antibody

based on 2 citations in multiple journalsHsc70 Antibody24.1 4
Catalog #: 3095
SKU-Size Size Price Qty
3095-30T 30 µg
$89.00
3095-100 100 µg
$280.00
More Sizes Get Quote

Product Details

Antibody Target Hsp70
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide surrounding amino acid 559 of human Hsc70
Accession # P11142
Gene ID 3312
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit anti-Hsc70 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification Affinity purified
Species Reactivity Human, mouse, rat, monkey, hamster, rabbit, bovine
Application Western blot, Immunohistochemistry
Application & Usage Western blot analysis (0.5-4 µg/ml) and in Immunohistochemistry. However, the optimal conditions should be determined individually. The antibody detects a 71 kDa Hsc70. A ~40 kDa band can also be detected in human samples. Jurkat cell lysate (Cat.# 2401-1
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The 70 kDa heat shock cognate protein, Hsc70, is part of the Hsp70 family. The family includes both cognate members and highly inducible isoforms. Members of the Hsp70 family are molecular chaperones which are involved in many cellular functions such as protein folding, transport, maturation and degradation.


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Yim Y. et. al. Endocytosis and clathrin-uncoating defects at synapses of auxilin knockout mice PNAS, Mar 2010; 107: 4412 - 4417.
Sugita, M., et al. (2004) Mol. Pharmacol. 66: 1248-1259.
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