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Honokiol

A NF-kappaB modulator
Catalog #: 1762
SKU-Size Size Price Qty
1762-10 10 mg
$70.00
1762-50 50 mg
$275.00
More Sizes Get Quote

Product Details

Alternate Name 2-(4-hydroxy-3-prop-2-enyl-phenyl)- 4-prop-2-enyl-phenol; HNK; Houpa
Appearance White solid
CAS # 35354-74-6
Molecular Formula C₁₈H₁₈O₂
Molecular Weight 266.33
Purity ≥97% by HPLC
Solubility DMSO (10 mg/ml) or EtOH
SMILES C=CCC1=CC(=C(C=C1)O)C2=CC(=C(C=C2)O)CC=C
InChi InChI=1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H2
InChi Key FVYXIJYOAGAUQK-UHFFFAOYSA-N
PubChem CID 72303
MDL Number MFCD00016674
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Present as an active principle in the plant Magnolia grandiflora. Displays anxiolytic, antithrombotic, anti-tumor properties, etc. modulates the NF-κB activation pathway, an upstream effector VEGF, COX-2, and MCL1, all significant pro-angiogenic and survival factors. Honokiol induces caspase-dependent apoptosis in a TRAIL-mediated manner, and potentiates the pro-apoptotic effects of doxorubicin and other etoposides.


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