Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

Homocysteine α,γ-Lyase (rHCYase), Active, Recombinant

Enzyme that can metabolize homocysteine into α-keto butyrate, hydrogen sulfide and ammonia.
Catalog #: P1117

Product Details

Cat # +Size P1117-200
Size 200 μg
Alternate Name Homocysteine α,γ-Lyase (rHCYase)
Gene Symbol mgl1
Accession # O15564
Source E. Coli
Appearance Lyophilized
Physical Form Description Lyophilized form proprietary buffer
Molecular Weight 43 kDa
Purity by SDS-PAGE > 95%
Biological Activity Specific activity is ≥ 5 mU/mg in which one Unit enzyme converts 1 µmole of homocysteine into hydrogen sulfide, per minute at 25 ºC and pH 8.1 in the presence of pyridoxal phosphate
Reconstitution Instructions Reconstitute in 40 mM Sodium phosphate buffer, pH 8.1.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans


Recombinant Homocysteine α,γ-lyase is a pyridoxal-5’-phosphate dependent enzyme. It is a mutant of homocysteinase from Trichomonas vaginalis encoded by mgl1 gene, containing three point mutations, such as; Phe47Leu, Asp172Glu, Ser308Tyr. Its native molecular mass is 170 kD, with four seemingly identical subunits, each with molecular mass of 43-45 kD. The enzyme can metabolize homocysteine into α-keto butyrate, hydrogen sulfide and ammonia.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.