Product Details
| Cat # +Size | 6790-50 |
|---|---|
| Size | 50 μl |
| Antibody Target | HLA-A |
| Alternate Name | HLA-A; HLAA; HLA class I histocompatibility antigen, A-3 alpha chain; MHC class I antigen A*3 |
| Host | Mouse |
| Antibody Type | Monoclonal |
| Isotype | Mouse IgG1, 2bk |
| Immunogen | This HLA-A antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 70-99 amino acids from human HLA-A. |
| Accession # | P05534 |
| Gene ID | N/A |
| Appearance | Colorless liquid |
| Formulation | Crude ascites with 0.09% (W/V) sodium azide. |
| Purification | Protein G purification followed by dialysis against PBS |
| Species Reactivity | Human, Mouse. |
| Application | Western blot. |
| Positive Control | Western blot: Ramos cell lysate. |
| Application & Usage | WB: 1:500 – 1:1000. |
| Handling | The antibody solution should be gently mixed before use. |
| Storage Conditions | -20 °C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Major histocompatibility complex (MHC) molecules form an integral part of the immune response system. They are cell-surface receptors that bind peptides and present them to T lymphocytes. Human leukocyte antigens (HLAs) are polymorphic members of the MHC family that are specifically involved in the presentation of antigens to the T cell receptor. There are two classes of HLA antigens: class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). Class I molecules are expressed in nearly all cells and play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum. The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes. HLA-A encodes a membrane anchored heavy chain which hetero-dimerizes with a light chain (b-2-Microglobulin) to form MHC-I. Polymorphisms yield hundreds of HLA-A alleles.
Why buy BioVision Products?
 |
 |
 |
 |
Innovation |
Affordability |
Global Presence |
Technical Support |
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways. |
BioVision is committed to providing the highest quality products at a competitive price. |
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery. |
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently. |
