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Histone H3 (phospho-Ser28) (Clone 117C826) Antibody

Monoclonal antibody to detect Histone H3 in human samples
Catalog #: 6119
$245.00

Product Details

Cat # +Size 6119-50
Size 50 μg
Antibody Target Histone H3
Alternate Name PHH3, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/I, Histone H3/j, Histone H3/k, Histone H3/l
Host Mouse
Antibody Type Monoclonal
Isotype Mouse IgG
Immunogen Synthetic peptide from human histone H3
Accession # P68431
Gene ID 8350
Appearance Colorless liquid
Formulation 50 µg of antibody in 100 µl PBS containing 0.05% sodium azide.
Purification Protein G purified
Species Reactivity Human
Application Western blot
Positive Control Western blot: Untreated Jurkat cell lysate, FAS-antibody treated Jurkat cell lysate
Application & Usage Western blot: 2 µg/ml. However, the optimal conditions should be determined individually.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The phosphorylation of histone H3 plays an important role in gene expression, chromatin remodeling, chromosome condensation, and cell division. Histone H3 phosphorylation may initiate at different phases of the cell division in different organisms, but metaphase chromosomes are always found to be heavily phosphorylated. H3 phosphorylation at serine 28 is coupled with mitotic chromosome condensation in diverse mammalian cell lines.


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