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Histone H2A Peptide

Substrate for HAT assays
Catalog #: 7145
SKU-Size Size Price Qty
7145-1 1 mg
$115.00
7145-5 5 mg
$295.00
More Sizes Get Quote

Product Details

Highlights SOURCE: Synthetic
PURITY: ≥ 98% by HPLC MOLECULAR WEIGHT: ~ 2.08 kDa
FORM: Lyophilized powder
FORMULATION: Peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
RECONSTITUTION: Centrifuge the vial prior to opening. Reconstitute 1 mg/ml in dH2O. Avoid repeated freeze-thaw cycles. Store at -20°C for 6 months. For use with BioVision assays K334-100, K336-100 or K346-100, reconstitute H2A peptide in assay buffer at 20 mg/ml concentration and use 2 µl/assay.
AMINO ACID SEQUENCE: SGRGKQGGKARAKAKTRSSR.
KEY APPLICATIONS: The suggested applications include usage as a substrate for histone modified enzymes, HAT assays (K334-100, K336-100, K346-100), Immunoprecipitation, affinity precipitation, etc.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. This synthetic peptide covers 1-20 amino acids of the protein. H2A has lately been found to be efficient in DNA delivery into a number of cell lines.


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