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Product Details
| Highlights | SOURCE: Synthetic PURITY: ≥ 98% by HPLC MOLECULAR WEIGHT: ~ 2.08 kDa FORM: Lyophilized powder FORMULATION: Peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form. RECONSTITUTION: Centrifuge the vial prior to opening. Reconstitute 1 mg/ml in dH2O. Avoid repeated freeze-thaw cycles. Store at -20°C for 6 months. For use with BioVision assays K334-100, K336-100 or K346-100, reconstitute H2A peptide in assay buffer at 20 mg/ml concentration and use 2 µl/assay. AMINO ACID SEQUENCE: SGRGKQGGKARAKAKTRSSR. KEY APPLICATIONS: The suggested applications include usage as a substrate for histone modified enzymes, HAT assays (K334-100, K336-100, K346-100), Immunoprecipitation, affinity precipitation, etc. |
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| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. This synthetic peptide covers 1-20 amino acids of the protein. H2A has lately been found to be efficient in DNA delivery into a number of cell lines.
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