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Hh Signaling Pathway Antagonist

A hedgehog (Hh) signaling pathway inhibitor
Catalog #: 1659

Product Details

Cat # +Size 1659-1
Size 1 mg
Alternate Name N-[4-Chloro-3-(trifluoromethyl)phenyl]-N’-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl-urea
Appearance White to off-white solid
CAS # 330796-24-2
Molecular Formula C₂₃H₁₅ClF₄N₄O₂
Molecular Weight 490.84
Purity ≥97% by HPLC
Solubility DMSO
SMILES C1=CC=C2C(=C1)C(=O)N(C(=N2)CNC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)C4=CC=C(C=C4)F
InChi InChI=1S/C23H15ClF4N4O2/c24-18-10-7-14(11-17(18)23(26,27)28)30-22(34)29-12-20-31-19-4-2-1-3-16(19)21(33)32(20)15-8-5-13(25)6-9-15/h1-11H,12H2,(H2,29,30,34)
PubChem CID 9913498
Handling Protect from air and light
Storage Conditions 4°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.


Cell-permeable. A potent antagonist of the Hedgehog (Hh) signaling pathway (IC₅₀ = 70 nM).

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