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Hh-Ag1.5

A Hedgehog (Hh) pathway agonist
Catalog #: B2160

In stock

SKU-Size Size Price Qty
B2160-1 1 mg
$165.00
B2160-5 5 mg
$650.00
More Sizes Get Quote

Product Details

Alternate Name 3-chloro-4,7-difluoro-N-(4-(methylamino)cyclohexyl)-N-(3-(pyridin-4-yl)benzyl)benzo[b]thiophene-2-carboxamide
Appearance Yellow solid
CAS # 612542-14-0
Molecular Formula C₂₈H₂₆N₃OS
Molecular Weight 526.04
Purity ≥98% by HPLC
Solubility DMSO (>20 mg/ml)
SMILES CN[[email protected]@H]1CC[[email protected]](CC1)N(Cc2cccc(c2)c3ccncc3)C(=O)c5sc4c(F)ccc(F)c4c5Cl
InChi InChI=1S/C28H26ClF2N3OS/c1-32-20-5-7-21(8-6-20)34(16-17-3-2-4-19(15-17)18-11-13-33-14-12-18)28(35)27-25(29)24-22(30)9-10-23(31)26(24)36-27/h2-4,9-15,20-21,32H,5-8,16H2,1H3/t20-,21-
InChi Key RXZDWPYJFCAZCW-MEMLXQNLSA-N
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Hh-Ag 1.5 is a potent and selective agonist of the Hh pathway (Smoothened/Smo agonist) (EC₅₀ = 1 nM).


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