Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

New

HDAC, EGFR & HER2 inhibitor

An HDAC, EGFR, and HER2 Inhibitor
Catalog #: B2933
SKU-Size Size Price Qty
B2933-5 5 mg
$125.00
B2933-25 25 mg
$495.00
More Sizes Get Quote

Product Details

Alternate Name 7-[4-(3-Chloro-4-fluoro-phenylamino)-7-methoxy-quinazolin-6-yloxy]-heptanoic acid hydroxyamide; 7-((4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)-N-hydroxyheptanamide
Appearance Solid
CAS # 1012054-55-5
Molecular Formula C₂₂H₂₄ClFN₄O₄
Molecular Weight 462.9
Purity 95%
Solubility Soluble in DMSO
SMILES O=C(NO)CCCCCCOC1=CC2=C(NC3=CC=C(F)C(Cl)=C3)N=CN=C2C=C1OC
InChi InChI=1S/C22H24ClFN4O4/c1-31-19-12-18-15(11-20(19)32-9-5-3-2-4-6-21(29)28-30)22(26-13-25-18)27-14-7-8-17(24)16(23)10-14/h7-8,10-13,30H,2-6,9H2,1H3,(H,28,29)(H,25,26,27)
InChi Key RQYVKBOWLRVISJ-UHFFFAOYSA-N
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

HDAC, EGFR, and HER2 Inhibitor is a multitargeted inhibitor of histone deacetylase (HDAC), epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2) with IC₅₀ values of 6.5 nM, 3.1 nM and 19 nM respectively. It inhibits the growth of different cell lines such as HCC827, H358, H460 with IC₅₀ values of 0.93 μM, 0.71 μM, 0.90 μM respectively.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.