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Harzianum A

A trichothecene fungal metabolite
Catalog #: B3226
$225.00

Product Details

Cat # +Size B3226-1
Size 1 mg
Alternate Name (2E,4E,6Z)-8-oxo-8-[(1S,2R,7R,9R,11R,12S)-1,2,5-trimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-11-yl]oxyocta-2,4,6-trienoic acid
Peptide Sequence N/A
Appearance Off-white solid
CAS # 156250-74-7
Molecular Formula C₂₃H₂₈O₆
Molecular Weight 400.4
Purity ≥95%
Solubility DMSO
SMILES CC1=C[[email protected]]2([H])[[email protected]](C3(C)C4(OC4)[[email protected]](C[[email protected]]3OC(/C=C\C=C\C=C\C(O)=O)=O)([H])O2)(C)CC1
InChi InChI=1S/C23H28O6/c1-15-10-11-21(2)16(12-15)28-18-13-17(22(21,3)23(18)14-27-23)29-20(26)9-7-5-4-6-8-19(24)25/h4-9,12,16-18H,10-11,13-14H2,1-3H3,(H,24,25)/b5-4+,8-6+,9-7-/t16-,17-,18-,21+,22?,23?/m1/s1
InChi Key FVRDNLIUSWSBCT-WNNZSMTESA-N
PubChem CID 6444304
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Harzianum A is a trichothecene fungal metabolite isolated from T. harzianum. It is cytotoxic to HeLa, MCF-7, and HT-1080 cells (IC50s = 5.07, 10.13, and 0.65 μg/ml, respectively) and displays antifungal activity.


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