Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]


A MAO-A and DYRK inhibitor
Catalog #: 2561
SKU-Size Size Price Qty
2561-50 50 mg
2561-250 250 mg
More Sizes Get Quote

Product Details

Alternate Name 7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole
Appearance White to off-white solid
CAS # 442-51-3
Molecular Formula C₁₃H₁₂N₂O
Molecular Weight 212.25
Purity ≥98% by titration
Solubility DMSO (>20 mg/ml)
InChi InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3
PubChem CID 5280953
MDL Number MFCD00004958
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Harmine is a potent and specific inhibitor of both the kinase activity and autophosphorylation of tyrosine during translation DYRK1A (IC₅₀’s: DYRKA1A = 33 nM; DYRKA1B = 166 nM; DYRK2 = 1.9 µM; DYRK4 = 80 µM). Inhibits self-renewal and promotes differentiation of glioblastoma stem-like cells(GSLC’s) possibly via inhibition of Akt phosphorylation. Selective competitive and reversible inhibitor of MAO-A (IC₅₀ = 8 µM). Also regulates PPARγ expression and displays antidiabetic activity.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.