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HA14-1

A potent, cell-permeable Bcl-2 inhibitor with potential anticancer activity.
Catalog #: B1832
SKU-Size Size Price Qty
B1832-5 5 mg
$135.00
B1832-25 25 mg
$540.00
More Sizes Get Quote

Product Details

Alternate Name 2-Amino-6-bromo-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester
Appearance White solid
CAS # 65673-63-4
Molecular Formula C₁₇H₁₇BrN₂O₅
Molecular Weight 409.23
Purity ≥98% by HPLC
Solubility DMSO (>35 mg/ml) or EtOH (>30 mg/ml)
SMILES CCOC(=O)C1=C(OC2=C(C1C(C#N)C(=O)OCC)C=C(C=C2)Br)N
InChi InChI=1S/C17H17BrN2O5/c1-3-23-16(21)11(8-19)13-10-7-9(18)5-6-12(10)25-15(20)14(13)17(22)24-4-2/h5-7,11,13H,3-4,20H2,1-2H3
InChi Key SXJDCULZDFWMJC-UHFFFAOYSA-N
PubChem CID 3549
MDL Number MFCD00218213
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

HA14-1 is a potent, cell-permeable Bcl-2 inhibitor with potential anticancer activity. HA14-1 induces apoptosis in various human cancer cells.  Also binds to the antiapoptotic Blc-2 proteins Bcl-XL and Bcl-w.


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