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H3K9me3S10p Antibody

Polyclonal Antibody to detect H3K9me3S10p in human samples.
Catalog #: 6808
$245.00

Product Details

Cat # +Size 6808-50
Size 50 μl
Antibody Target H3K9me3S10p
Alternate Name Histone H3
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen KLH-conjugated synthetic peptide of Histone H3 containing trimethylated lysine 9 and the phosphorylated serine 10.
Accession # P68431
Gene ID 8350
Appearance Colorless liquid
Formulation In PBS with 0.05% (W/V) sodium azide.
Purification Whole antiserum from rabbit
Species Reactivity Human.
Application Western blot, IF, ELISA, ChIP, Dot blot.
Positive Control IF: HeLa cells, WB: HeLa cells, ELISA: Antigen, ChIP: HeLa cells, Dot blot: Histone peptides
Application & Usage IF: 1:500, WB: 1:500, ELISA: 1:1000 – 1:10000, Dot Blot: 1:1000, ChIP: 5 µl/ChIP.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called “histone code”. Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases.


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