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H-7 dihydrochloride

A protein kinase inhibitor
Catalog #: 9543
SKU-Size Size Price Qty
9543-5 5 mg
$115.00
9543-25 25 mg
$455.00
More Sizes Get Quote

Product Details

Alternate Name (±)-1-(5-Isoquinolinesulphonyl)-2-methylpiperazine dihydrochloride
Peptide Sequence N
Appearance White solid
CAS # 108930-17-2
Molecular Formula C₁₄H₁₇N₃O₂S.2HCl
Molecular Weight 364.29
Purity ≥98% by HPLC
Solubility DMSO (>20 mg/ml) or H₂O (>20 mg/ml)
SMILES CC1CNCCN1S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl.Cl
InChi InChI=1S/C14H17N3O2S.2ClH/c1-11-9-16-7-8-17(11)20(18,19)14-4-2-3-12-10-15-6-5-13(12)14;;/h2-6,10-11,16H,7-9H2,1H3;2*1H
InChi Key OARGPFMFRLLKPF-UHFFFAOYSA-N
PubChem CID 73332
MDL Number MFCD00036961
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

H-7 is a Protein kinase inhibitor that inhibits the activity of PKA, PKC, PKG and MLCK with IC₅₀ values of 3.0, 6.0, 5.8 and 97.0 µM, respectively.


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