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A potent and specific PPARβ/δ agonist
Catalog #: B1100
SKU-Size Size Price Qty
B1100-5 5 mg
B1100-25 25 mg
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Product Details

Alternate Name [4-[[[2-[3-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy]acetic acid
Appearance White Solid
CAS # 317318-84-6
Molecular Formula C₂₁H₁₇F₄NO₃S₂
Molecular Weight 471.49
Purity ≥98% by HPLC
Solubility DMSO (>40 mg/ml)
InChi InChI=1S/C21H17F4NO3S2/c1-11-7-14(4-6-17(11)29-9-19(27)28)30-10-18-12(2)26-20(31-18)13-3-5-15(16(22)8-13)21(23,24)25/h3-8H,9-10H2,1-2H3,(H,27,28)
PubChem CID 9934458
MDL Number MFCD07369423
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


GW 0742 is a potent and selective PPARδ agonist (EC₅₀ = 1.1 nM) that displays 1,000-fold selectivity over other human PPAR subtypes. Therapeutically has shown to have effect on pulmonary damage, inflammatory and apoptotic parameters in mice. It increases the rate of fatty acid oxidation and provides ischemia /reperfusion injury protection in cardiomyocytes. It has been reported to have neuroprotective properties and enhances interleukin-6 (IL-6), IL-8 expression.

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