Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

New

GSK-626616

A potent and selective DYRK inhibitor
Catalog #: B2452

In stock

SKU-Size Size Price Qty
B2452-5 5 mg
$175.00
B2452-25 25 mg
$695.00
More Sizes Get Quote

Product Details

Alternate Name (5Z)-2-[(2,6-Dichlorophenyl)amino]-5-(6-quinoxalinylmethylene)-4(5H)-thiazolone
Appearance Pale orange solid
CAS # 1025821-33-3
Molecular Formula C₁₈H₁₀Cl₂N₄OS
Molecular Weight 401.27
Purity ≥98% by HPLC
Solubility >35 mg/ml DMSO
SMILES C1=CC(=C(C(=C1)Cl)N=C2NC(=O)C(=CC3=CC4=NC=CN=C4C=C3)S2)Cl
InChi InChI=1S/C18H10Cl2N4OS/c19-11-2-1-3-12(20)16(11)23-18-24-17(25)15(26-18)9-10-4-5-13-14(8-10)22-7-6-21-13/h1-9H,(H,23,24,25)/b15-9-
InChi Key RJPNRXFBYZVRIB-DHDCSXOGSA-N
PubChem CID 135416229
MDL Number MFCD31689261
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

GSK-626616 is a potent and selective DYRK inhibitor (IC₅₀ = 0.7 nM); inhibits other members of the DYRK family, e.g., DYRK1A and DYRK2, with similar potency. Displays ~20-fold selectivity over casein kinase 2 and negligible activity against a panel of 451 kinases screened.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.