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GSK-3b Antibody

Catalog #: 3494
SKU-Size Size Price Qty
3494-30T 30 µg
$89.00
3494-100 100 µg
$255.00
More Sizes Get Quote

Product Details

Antibody Target GSK-3b
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Active recombinant human GSK-3β
Accession # NP_002084
Gene ID 2932
Appearance Colorless liquid
Concentration 0.2 mg/ml
Formulation 100 µg (0.2 mg/ml) affinity purified rabbit polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification Affinity purified
Species Reactivity Human, mouse, rat
Application Western blot, Immunohistochemistry
Application & Usage Western blot analysis (0.5-4 µg/ml), in Immunohistochemistry (10-30 µg/ml). However, the optimal conditions should be determined individually.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Glycogen synthase kinase 3 (GSK-3) is a serine/threonine protein kinase that has been implicated in the regulation of cell fate and in the Wnt signaling pathway. GSK-3 plays an important role in the PI3 kinase and Akt mediated cell survival pathways, and its activity can be inhibited by Akt-mediated phosphorylation at Ser21 of GSK-3α and Ser9 of GSK-3β. GSK-3 has also been implicated in alzheimer’s disease. Six Tau protein isoforms have been identified, all of which are phosphorylated by GSK-3.


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