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GSK-3484862

A non-covalent Dnmt1 inhibitor
Catalog #: B3326
SKU-Size Size Price Qty
B3326-5 5 mg
$135.00
B3326-25 25 mg
$535.00
More Sizes Get Quote

Product Details

Alternate Name (2R)-2-[3,5-dicyano-6-(dimethylamino)-4-ethylpyridin-2-yl]sulfanyl-2-phenylacetamide GSKMI-714
Appearance Solid
CAS # 2170136-65-7
Molecular Formula C₁₉H₁₉N₅OS
Molecular Weight 365.45
Purity ≥98%
Solubility >20 mg/ml DMSO
SMILES CCC1=C(C(=NC(=C1C#N)SC(C2=CC=CC=C2)C(=O)N)N(C)C)C#N
InChi InChI=1S/C19H19N5OS/c1-4-13-14(10-20)18(24(2)3)23-19(15(13)11-21)26-16(17(22)25)12-8-6-5-7-9-12/h5-9,16H,4H2,1-3H3,(H2,22,25)/t16-/m1/s1
InChi Key KIEQQZZDWUNUQK-MRXNPFEDSA-N
PubChem CID 132233666
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

GSK3484862 (GSKMI-714) is a selective, reversible, non-covalent DNMT1 (DNA Methyltransferase 1) inhibitor. Potently inhibits the methyltransferase activity of DNMT1, but not DNMT family members DNMT3A or DNMT3B.


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