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GSK-2814338

A potent Lp-PLA2 inhibitor
Catalog #: B2426
SKU-Size Size Price Qty
B2426-5 5 mg
$145.00
B2426-25 25 mg
$575.00
More Sizes Get Quote

Product Details

Alternate Name GSK2814338, Lp-PLA2 -IN-1, 8-((3,5-difluoro-4-((6-(trifluoromethyl)pyridin-3-yl)oxy)benzyl)oxy)-1-methyl-1,2,3,4-tetrahydro-6H-pyrimido[1,6-a]pyrimidin-6-one
Appearance Crystalline solid
CAS # 1420367-28-7
Molecular Formula C₂₁H₁₇F₅N₄O₃
Molecular Weight 468.38
Purity ≥98% by HPLC
Solubility in DMSO
SMILES CN1CCCN2C1=CC(=NC2=O)OCC3=CC(=C(C(=C3)F)OC4=CN=C(C=C4)C(F)(F)F)F
InChi InChI=1S/C21H17F5N4O3/c1-29-5-2-6-30-18(29)9-17(28-20(30)31)32-11-12-7-14(22)19(15(23)8-12) 33-13-3-4-16 (27-10-13)21(24,25)26/h3-4,7-10H,2,5-6,11H2,1H3
InChi Key QJIGPJZJKXZSNF-UHFFFAOYSA-N
PubChem CID 71236597
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

GSK-2814338 is a potent Lp-PLA2 inhibitor useful for the treatment of atherosclerosis and Alzheimer's disease


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