GSK-3β Inhibitor, TWS119

A GSK-3β inhibitor
Catalog #: 1655 | abID: ab142075

Product Details

abID ab142075
Cat # +Size 1655-2
Size 2 mg
Alternate Name 3-[[6-(3-Aminophenyl)-1H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-phenol
Appearance Slightly pink solid
CAS # 601514-19-6
Molecular Formula C₁₈H₁₄N₄O₂
Molecular Weight 318.33
Purity ≥95% by HPLC
Solubility DMSO (20 mg/ml)
InChi InChI=1S/C18H14N4O2/c19-12-4-1-3-11(7-12)16-9-15-17(22-16)20-10-21-18(15)24-14-6-2-5-13(23)8-14/h1-10,23H,19H2,(H,20,21,22)
PubChem CID 9549289
MDL Number MFCD09037535
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


A potent inhibitor of GSK-3β (Glycogen synthase kinase-3β) (IC₅₀ = 30 nM). At 400 nM, TWS119 induces neurogenesis in murine embryonic stem cells making it a useful tool to regulate stem cell self-renewal and differentiation.

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