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GSK-3β, human recombinant

based on 1 citations in multiple journalsGSK-3β, human recombinant14.1 4
A phosphorylating and an inactivating agent of glycogen synthase
Catalog #: 7004
SKU-Size Size Price Qty
7004-10 10 μg
$185.00
7004-100 100 μg
$445.00
7004-1000 1 mg
$2,950.00
More Sizes Get Quote

Product Details

Alternate Name GSK, Glycogen synthase kinase-3 (GSK-3)
Gene Symbol GSK3B
Gene ID 2932
Accession # P49841
Source E. coli.
Appearance Lyophilized powder
Physical Form Description Lyophilized from 2 mg/ml in 0.1 M NH4CO3
Molecular Weight 53.0-56.0 kDa
Purity by SDS-PAGE ≥90%
Reconstitution Instructions Reconstitute to 1 mg/ml in PBS containing 15% glycerol. The solution should be stored at –70°C, stable for up to 3 months.
Handling Centrifuge the vial prior to opening.
Storage Conditions -70°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans

Details

Glycogen synthase kinase-3 (GSK-3) is a serine/theronine kinase that was first characterized by its role in intermediary metabolism. In mammals, serine kinase is encoded by two related genes called GSK-3α (51 kDa) and GSK-3β (46 kDa). GSK-3 has been implicated in the regulation of the c-JuP-1 transcription factor and other intracellular signaling pathways.


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Morel, S. et. al. Unexpected role for the human Cx37 C1019T polymorphism in tumour cell proliferation. Carcinogenesis, Nov 2010; 31: 1922 - 1931
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