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A highly specific and potent inhibitor of PDK1 (3-Phosphoinositide dependent protein kinase-1)
Catalog #: B1555
SKU-Size Size Price Qty
B1555-5 5 mg
B1555-25 25 mg
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Product Details

Alternate Name (3S,6R)-1-[6-(3-Amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-methyl-3-piperidinecarboxamide
Appearance Light yellow solid
CAS # 1227911-45-6
Molecular Formula C₂₅H₃₄N₈O
Molecular Weight 462.59
Purity ≥98% by HPLC
Solubility DMSO (>40 mg/ml) or EtOH (>30 mg/ml)
InChi InChI=1S/C25H34N8O/c1-15-8-9-17(24(34)28-18-6-4-3-5-7-18)14-33(15)22-13-20(29-25(27-2)30-22)16-10-11-19-21(12-16)31-32-23(19)26/h10-13,15,17-18H,3-9,14H2,1-2H3,(H,28,34)(H3,26,31
PubChem CID 46215815
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


GSK-2334470 is a highly specific and potent inhibitor of PDK1 (3-Phosphoinositide dependent protein kinase-1) (IC₅₀ = 10 nM). It does not suppress activity on other 96 kinases, including Aurora, ROCK, p38 MAPK and PI3K.

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