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GS-9973

A potent Syk inhibitor
Catalog #: 2669

In stock

SKU-Size Size Price Qty
2669-1 1 mg
$85.00
2669-5 5 mg
$335.00
More Sizes Get Quote

Product Details

Alternate Name 6-(1H-indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine; Entospletinib
Appearance Pale yellow solid
CAS # 1229208-44-9
Molecular Formula C₂₃H₂₁N₇O
Molecular Weight 411.5
Purity ≥98% by HPLC
Solubility DMSO (>50 mg/ml)
SMILES C1COCCN1C2=CC=C(C=C2)NC3=NC(=CN4C3=NC=C4)C5=CC6=C(C=C5)C=NN6
InChi InChI=1S/C23H21N7O/c1-2-17-14-25-28-20(17)13-16(1)21-15-30-8-7-24-23(30)22(27-21)26-18-3-5-19(6-4-18)29-9-11-31-12-10-29/h1-8,13-15H,9-12H2,(H,25,28)(H,26,27)
InChi Key XSMSNFMDVXXHGJ-UHFFFAOYSA-N
PubChem CID 59473233
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

GS-9973 is a potent and highly selective Syk (spleen tyrosine kinase) inhibitor (IC₅₀ = 7.7 nM).


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