Granzyme A, Human Recombinant

Serine proteases which induce apoptosis
Catalog #: 4279 | abID: ab285546

Product Details

abID ab285546
Alternate Name CTL tryptase, Cytotoxic T-lymphocyte proteinase 1, Fragmentin-1, Granzyme-1, Hanukkah factor, H factor, HF
Gene Symbol GZMA
Gene ID 3001
Accession # P12544
Source HEK 293 cells
Appearance Lyophilized protein
Physical Form Description Recombinant Granzyme A is lyophilized from PBS
Molecular Weight 26 kDa
Purity by SDS-PAGE > 90%
Endotoxin Level < 1.0 EU/μg of protein as determined by LAL method
Reconstitution Instructions Reconstitute in sterile deionized water for a stock solution.
Amino Acid Sequence Recombinant Human Granzyme A is expressed from HEK 293 cells. Target protein is expressed with sequence (Glu27-Val262) of Human granzyme A (Uniprot #P12544) fused with a C-terminal His tag.
Handling Centrifuge the vial prior to opening.
Storage Conditions Aliquot and store at -20 °C or -80 °C. Avoid repeated freeze thaw cycles.
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans


Granzyme A is a member of the granzyme family. Granzyme A is the most abundant serine protease in cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. Granzyme A has a specific function in CTL and NK cells. It induces caspase-independent cell death when introduced into target cells by perforin. Human granzyme A is synthesized as a precursor (262 residues) with a signal peptide (residues 1-26), a propeptide (residues 27-28) and a mature chain (residues 29-262).

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.