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GM-CSF, rat recombinant

based on 3 citations in multiple journalsGM-CSF, rat recombinant34.1 4
A cytokine functioning as a white blood cell growth factor
Catalog #: 4102
SKU-Size Size Price Qty
4102-10 10 μg
$190.00
4102-100 100 μg
$695.00
4102-1000 1 mg
$3,450.00
More Sizes Get Quote

Product Details

Alternate Name Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-α, Colony-stimulating factor, Molgramostin, Sargramostim
Gene Symbol CSF2
Gene ID 116630
Accession # P48750
Source E. coli
Appearance Lyophilized protein
Physical Form Description Sterile filtered and lyophilized from 10 mM Tris, pH 8.5.
Molecular Weight 14.5 kDa
Purity by SDS-PAGE ≥98%
Purity by ≥98%
Endotoxin Level <0.1 ng/μg
Biological Activity The ED₅₀ determined by the dose-dependent stimulation of the proliferation of murine FDC-P1 cells is <0.01 ng/ml, corresponding to a specific activity of >1 x 10⁸ units/mg.
Reconstitution Instructions Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers or stored at 4°C for 1 week or –20°C for future use.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Rat GM-CSF (Granulocyte Macrophage Colony stimulating Factor) is a potent species-specific stimulator of bone marrow cells. GM-CSF stimulates precursor cells of granulocytes, macrophages and eosinophils. Recombinant rat GM-CSF is a 14.5 kDa globular protein consisting of 128 amino acid residues


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Kim, Y. J. et. al. Phagocytosis, a Potential Mechanism for Myeloid-Derived Suppressor Cell Regulation of CD8+ T Cell Function Mediated through Programmed Cell Death-1 and Programmed Cell Death-1 Ligand Interaction. J. Immunol., Sep 2011; 187: 2291 - 2301.
Fukuda S et al. (2007) Blood 10.1182/blood-2006-06-0314012.
Chen M et al. (2007) Blood 109: 4360-4367.
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