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A NADPH oxidase 4 (NOX-4) inhibitor
Catalog #: B2340

In stock

SKU-Size Size Price Qty
B2340-5 5 mg
B2340-25 25 mg
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Product Details

Alternate Name Ethyl 2-[[2-[4-(furan-2-carbonyl)piperazin-1-yl]acetyl]amino]-5,6-dihydro-4H-cyclopenta-[b]thiophene-3-carboxylate,GLX351322
Appearance Crystalline solid
CAS # 835598-94-2
Molecular Formula C₂₁H₂₅N₃O₅S
Molecular Weight 431.51
Purity ≥98% by HPLC
Solubility >5 mg/ml (DMSO)
InChi InChI=1S/C21H25N3O5S/c1-2-28-21(27)18-14-5-3-7-16(14)30-19(18)22-17(25)13-23-8-10-24(11-9-23)20(26)15-6-4-12-29-15/h4,6,12H,2-3,5,7-11,13H2,1H3,(H,22,25)
PubChem CID 2697686
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


GLX-351322 is a potent NADPH oxidase-4 (NOX-4) inhibitor. Displays selectivity for NOX-4 over NOX-2. GLX-351322 inhibits hydrogen peroxide production from tetracycline inducible NOX4-overexpressing cells (IC₅₀ = 5 µM).

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