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Glutamate Decarboxylase α (GAD α), E. coli Recombinant

Converts glutamate to gamma-aminobutyrate (GABA)
Catalog #: P1404
SKU-Size Size Price Qty
P1404-50 50 µU
$165.00
P1404-200 200 µU
$495.00
More Sizes Get Quote

Product Details

Alternate Name GAD-alpha, gadA, gadS
Gene Symbol gadA
Gene ID 948027
Accession # P69908
Source E. coli
Appearance Lyophilized powder
Physical Form Description Lyophilized
Molecular Weight 53.6 kDa with C-terminal 6X-His tag
Purity by SDS-PAGE >95% by SDS-PAGE
Reconstitution Instructions Reconstitute the lyophilized protein in 10% glycerol with 5 mM 2-Mercaptoethanol to a final concentration of 1.0 mU/ml and incubate the reconstituted protein at 25 °C for 15 minutes.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Glutamate Decarboxylase α is a pyridoxal 5′-phosphate dependent enzyme. GAD α catalyzes conversion of glutamate to GABA. Aberrant expressions of GAD α have been associated with diabetes and neurodegenerative diseases such as Alzheimers and Parkinson’s Disease.


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