Glumetinib is a potent and highly selective c-Met inhibitor
Catalog #: B2561 | abID:

Product Details

Alternate Name SC-C244, SCC244, 6-(1-Methyl-1H-pyrazol-4-yl)-1-[[6-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]sulfonyl]-1H-pyrazolo[4,3-b]pyridine, SCC 244
Peptide Sequence N/A
Appearance Crystalline solid
CAS # 1642581-63-2
Molecular Formula C₂₁H₁₇N₉O₂S
Molecular Weight 459.49
Purity ≥98% by HPLC
Solubility in DMSO
SMILES CN1C=C(C=N1)C2=CN3C(=NC=C3S(=O)(=O)N4C5=C(C=N4)N=CC(=C5)C6=CN(N=C6)C)C=C2
InChi InChI=1S/C21H17N9O2S/c1-27-11-16(7-24-27)14-3-4-20-23-10-21(29(20)13-14)33(31,32)30-19-5-15(6-22-18(19)9-26-30)17-8-25-28(2)12-17/h3-13H,1-2H3
PubChem CID 117797905
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Glumetinib (SCC-244) is a potent and highly selective inhibitor of c-Met kinase (IC₅₀ = 0.42 nM). Glumetinib displays subnanomolar potency against c-Met kinase activity and high selectivity versus 312 other tested protein kinases.

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