Glumetinib

Glumetinib is a potent and highly selective c-Met inhibitor
Catalog #: B2561 | abID:

Product Details

Alternate Name SC-C244, SCC244, 6-(1-Methyl-1H-pyrazol-4-yl)-1-[[6-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]sulfonyl]-1H-pyrazolo[4,3-b]pyridine, SCC 244
Peptide Sequence N/A
Appearance Crystalline solid
CAS # 1642581-63-2
Molecular Formula C₂₁H₁₇N₉O₂S
Molecular Weight 459.49
Purity ≥98% by HPLC
Solubility in DMSO
SMILES CN1C=C(C=N1)C2=CN3C(=NC=C3S(=O)(=O)N4C5=C(C=N4)N=CC(=C5)C6=CN(N=C6)C)C=C2
InChi InChI=1S/C21H17N9O2S/c1-27-11-16(7-24-27)14-3-4-20-23-10-21(29(20)13-14)33(31,32)30-19-5-15(6-22-18(19)9-26-30)17-8-25-28(2)12-17/h3-13H,1-2H3
InChi Key RYBLECYFLJXEJX-UHFFFAOYSA-N
PubChem CID 117797905
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Glumetinib (SCC-244) is a potent and highly selective inhibitor of c-Met kinase (IC₅₀ = 0.42 nM). Glumetinib displays subnanomolar potency against c-Met kinase activity and high selectivity versus 312 other tested protein kinases.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.