Product Details
| Cat # +Size | 7776-10 |
|---|---|
| Size | 10 μg |
| Alternate Name | Glucokinase, Hexokinase type IV, HK IV, Hexokinase-4, HK4, Hexokinase-D |
| Gene Symbol | GCK |
| Gene ID | 2645 |
| Accession # | P35557 |
| Source | E. coli. |
| Appearance | Liquid |
| Physical Form Description | 50 mM potassium phosphate pH 7.4, 50 mM sodium chloride, 0.5 mM DTT, 0.5 mM EDTA, and 2.5% glycerol. |
| Molecular Weight | 53.4 kDa |
| Purity by SDS-PAGE | ≥77% |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -80°C |
| Shipping Conditions | Dry Ice |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Glucose is phosphorylated to glucose-6-phosphate by glucokinases. This gene is alternatively spliced to generate three different forms of the enzyme; one found in the pancreas and two found in the liver. The main function of this gene is to regulate carbohydrate metabolism. Recombinant human liver Glucokinase (Accession# NP_277042)) has a C-terminal FLAG tag and has 474 amino acid residues. It can be useful for studies including enzyme kinetics, activator screening and kinase selectivity.
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