Glucokinase, human liver, recombinant

Plays a key role in the communication of cells with their microenvironment
Catalog #: 7776 | abID:

Product Details

Cat # +Size 7776-10
Size 10 μg
Alternate Name Glucokinase, Hexokinase type IV, HK IV, Hexokinase-4, HK4, Hexokinase-D
Gene Symbol GCK
Gene ID 2645
Accession # P35557
Source E. coli.
Appearance Liquid
Physical Form Description 50 mM potassium phosphate pH 7.4, 50 mM sodium chloride, 0.5 mM DTT, 0.5 mM EDTA, and 2.5% glycerol.
Molecular Weight 53.4 kDa
Purity by SDS-PAGE ≥77%
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not For Use in Humans.

Details

Glucose is phosphorylated to glucose-6-phosphate by glucokinases. This gene is alternatively spliced to generate three different forms of the enzyme; one found in the pancreas and two found in the liver. The main function of this gene is to regulate carbohydrate metabolism. Recombinant human liver Glucokinase (Accession# NP_277042)) has a C-terminal FLAG tag and has 474 amino acid residues. It can be useful for studies including enzyme kinetics, activator screening and kinase selectivity.


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