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Glibenclamide

An anti-diabetic agent
Catalog #: 1878
SKU-Size Size Price Qty
1878-500 500 mg
$70.00
1878-1000 1 g
$120.00
More Sizes Get Quote

Product Details

Alternate Name 5-Chloro-N-[4-(cyclohexylureidosulfonyl)phenethyl]-2-methoxybenzamide; Glyburide, N-p-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzenesulfonyl-N′-cyclohexylurea
Appearance White to off-white solid
CAS # 10238-21-8
Molecular Formula C₂₃H₂₈ClN₃O₅S
Molecular Weight 494
Purity ≥99% by HPLC
Solubility DMSO (100 mM) or EtOH (5 mM)
SMILES COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
InChi InChI=1S/C23H28ClN3O5S/c1-32-21-12-9-17(24)15-20(21)22(28)25-14-13-16-7-10-19(11-8-16)33(30,31)27-23(29)26-18-5-3-2-4-6-18/h7-12,15,18H,2-6,13-14H2,1H3,(H,25,28)(H2,26,27,29)
InChi Key ZNNLBTZKUZBEKO-UHFFFAOYSA-N
PubChem CID 3488
MDL Number MFCD00056625
Handling Protect from air and moisture
Storage Conditions 2-8°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

Cell-permeable. An anti-diabetic agent. ATP-sensitive potassium channel (KATP) blocker. Inhibits KATP currents in the pancreatic beta cells causing an increase in intracellular Ca2+ and insulin secretion.


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