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Ginsenoside Ro

A biologically active non-steroid glycoside
Catalog #: B3395
SKU-Size Size Price Qty
B3395-5 5 mg
$115.00
B3395-25 25 mg
$455.00
More Sizes Get Quote

Product Details

Alternate Name Chikusetsusaponin V (3β)-28-(β-D-glucopyranosyloxy)-28-oxoolean-12-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranosiduronic acid
Appearance White to light yellow solid
CAS # 34367-04-9
Molecular Formula C₄₈H₇₆O₁₉
Molecular Weight 957.12
Purity ≥98%
Solubility >50 mg/ml DMSO
SMILES CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)OC6C(C(C(C(O6)C(=O)O)O)O)OC7C(C(C(C(O7)CO)O)O)O)C)C)C2C1)C)C(=O)OC8C(C(C(C(O8)CO)O)O)O)C
InChi InChI=1S/C48H76O19/c1-43(2)14-16-48(42(61)67-40-35(58)31(54)29(52)24(20-50)63-40)17-15-46(6)21(22(48)18-43)8-9-26-45(5)12-11-27(44(3,4)25(45)10-13-47(26,46)7)64-41-37(33(56)32(55)36(65-41)38(59)60)66-39-34(57)30(53)28(51)23(19-49)62-39/h8,22-37,39-41,49-58H,9-20H2,1-7H3,(H,59,60)/t22-,23+,24+,25-,26+,27-,28+,29+,30-,31-,32-,33-,34+,35+,36-,37+,39-,40-,41+,45-,46+,47+,48-/m0/s1
InChi Key NFZYDZXHKFHPGA-QQHDHSITSA-N
PubChem CID 11815492
MDL Number MFCD01732056
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Ginsenoside Ro (Ro), a major saponin derived and isolated from Panax ginseng C.A. Meyer, displays multiple biological activities including anti-inflammatory, antithrombotic, and antiviral activities. It inhibits LPS-induced release of reactive oxygen species (ROS) and nitric oxide (NO) as well as inducible nitric oxide synthase (iNOS) and COX-2 protein expression in RAW 264.7 murine macrophages when used at a concentration of 200 μM. Also displays Ca2+-antagonistic antiplatelet effect with an IC50 of 155 μM.


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