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GFAP, Human Recombinant

A class-III intermediate filament that distinguishes astrocytes from other glial cells during the development of the central nervous system
Catalog #: P1364

In stock

$365.00

Product Details

Cat # +Size P1364-10
Size 10 µg
Alternate Name Glial Fibrillary Acidic Protein, GFAP
Gene Symbol GFAP
Gene ID 2670
Accession # P14136
Source E.coli
Appearance Lyophilized
Physical Form Description Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.25.
Purity by SDS-PAGE >95%
Endotoxin Level <1 EU/μg by LAL method
Reconstitution Instructions Reconstitute in sterile deionized water to a concentration of 100 µg/ml.
Amino Acid Sequence MGSSHHHHHHSSGLVPRGSHMLTCDLESLRGTNESLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRDGEVIKESKQEHKDVM
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Glial Fibrillary Acidic Protein (GFAP) is an intermediate filament (IF) protein which belongs to the intermediate filament family. GFAP is expressed in numerous cell types of the central nervous system (CNS), ependymal cells and phosphorylated by PKN1. GFAP, a class-III intermediate filament, is a cell-specific marker during the development of the central nervous system and distinguishes astrocytes from other glial cells. It is closely related to its non-epithelial family members, vimentin, desmin, and peripherin, which are all involved in the structure and function of the cell’s cytoskeleton. GFAP is thought to help to maintain astrocyte mechanical strength, as well as the shape of cells but its exact function remains poorly understood.


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