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GDNF, human recombinant

A promotor of dopamine uptake and survival of midbrain neurons
Catalog #: 4097
SKU-Size Size Price Qty
4097-10 10 μg
$180.00
4097-50 50 μg
$595.00
4097-1000 1 mg
$4,800.00
More Sizes Get Quote

Product Details

Alternate Name Glial-Derived Neurotrophic Factor, ATF-1, Astrocyte-derived trophic factor
Gene Symbol GDNF
Gene ID 2668
Accession # P39905
Source E. coli
Appearance Lyophilized protein
Physical Form Description Lyophilized from 10 mM Sodium Citrate + 150 mM NaCl, pH 4.0.
Molecular Weight 30.1 kDa
Purity by SDS-PAGE ≥98%
Purity by ≥98%
Endotoxin Level <0.1 ng/μg
Biological Activity The ED₅₀ as determined by the dose-dependent dopamine uptake by rat ventral mesencephalic cultures was found to be in the range of 4-8 ng/ml.
Reconstitution Instructions Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Human GDNF (Glial-Derived Neurotrophic Factor) is a 30.1 kDa protein that specifically promotes dopamine uptake and survival of midbrain neurons. GDNF is a disslphide-linked homodimer, formed by two identical 134 amino acids subunits.


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