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GDF9, human recombinant

based on 1 citations in multiple journalsGDF9, human recombinant14.1 4
A factor required for ovarian folliculogenesis
Catalog #: 4872
SKU-Size Size Price Qty
4872-20 20 μg
$205.00
4872-100 100 μg
$655.00
4872-1000 1 mg
$4,145.00
More Sizes Get Quote

Product Details

Alternate Name Growth/differentiation factor 9
Gene Symbol GDF-9
Gene ID 2661
Accession # O60383
Source E. coli
Appearance Lyophilized protein
Physical Form Description Sterile filtered and lyophilized with no additives
Molecular Weight 31.2 kDa
Purity by SDS-PAGE ≥98%
Purity by ≥98%
Endotoxin Level <0.1 ng/μg
Reconstitution Instructions Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
USAGE For Research Use Only! Not to be used in humans

Details

GDF-9 is a member of the TGF-β superfamily of growth and differentiation factors, and is highly homologous to GDF-3. Unlike most TGF-family members, GDF-9 and GDF-3 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. GDF-9 is expressed in oocytes and is required for normal ovarian folliculogenesis. Recombinant human GDF-9 is a 31.0 kDa non-disulfide-linked homodimer containing two 135 amino acid polypeptide chains with 6XHis on its N-terminus.


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Chang et al., Oocyte-derived BMP15 but not GDF9 down-regulates connexin43 expression and decreases gap junction intercellular communication activity in immortalized human granulosa cells. Mol. Hum. Reprod., May 2014; 20: 373 - 383.
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