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GDC0994

A selective inhibitor of ERK1 and ERK2
Catalog #: B1629

In stock

SKU-Size Size Price Qty
B1629-5 5 mg
$140.00
B1629-25 25 mg
$545.00
More Sizes Get Quote

Product Details

Alternate Name GDC0994; GDC 0994; GDC-0994; Ravoxertinib; RG7842; RG-7842; RG 7842; 1-[(1S)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]pyridin-2-one
Appearance Solid
CAS # 1453848-26-4
Molecular Formula C₂₁H₁₈ClFN₆O₂
Molecular Weight 440.86
Purity >98%
Solubility DMSO
SMILES CN1C(=CC=N1)NC2=NC=CC(=N2)C3=CC(=O)N(C=C3)C(CO)C4=CC(=C(C=C4)Cl)F
InChi 1S/C21H18ClFN6O2/c1-28-19(5-8-25-28)27-21-24-7-4-17(26-21)13-6-9-29(20(31)11-13)18(12-30)14-2-3-15(22)16(23)10-14/h2-11,18,30H,12H2,1H3,(H,24,26,27)/t18-/m1/s1
InChi Key RZUOCXOYPYGSKL-GOSISDBHSA-N
PubChem CID 71727581
MDL Number MFCD28143918
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

GDC-0994 is highly selective inhibitor of extracellular signal-regulated kinase (ERK), ERK1 and ERK2, with biochemical potency of 1.1 nM and 0.3 nM, respectively.


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