Gardiquimod

A selective ligand for human or mouse TLR7
Catalog #: 2002 | abID: ab141485

Product Details

abID ab141485
Alternate Name 1-(4-Amino-2-ethylaminomethylimidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol
Appearance White solid
CAS # 1020412-43-4
Molecular Formula C₁₇H₂₃N₅O
Molecular Weight 313.4
Purity ≥98% by HPLC
Solubility DMSO (>40 mg/ml)
SMILES CCNCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N
InChi InChI=1S/C17H23N5O/c1-4-19-9-13-21-14-15(22(13)10-17(2,3)23)11-7-5-6-8-12(11)20-16(14)18/h5-8,19,23H,4,9-10H2,1-3H3,(H2,18,20)
InChi Key FHJATBIERQTCTN-UHFFFAOYSA-N
PubChem CID 44592366
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A selective ligand for human or mouse Toll-like receptor 7 (TLR7). Induces the activation of NF-κB in HEK 293 cells expressing TLR7. Activates TLR8 only at high concentrations (3µg/ml). Gardiquimod is more active than Imiquimod (Cat. No. 1698-100).


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