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Gallein

Inhibitor of Gβ/γ signaling
Catalog #: B3391
SKU-Size Size Price Qty
B3391-50 50 mg
$95.00
B3391-250 250 mg
$375.00
More Sizes Get Quote

Product Details

Alternate Name 3',4',5',6'-Tetrahydroxyspiro[isobenzofuran-1(3H),9'-(9H)xanthen]-3-one
Appearance Black solid
CAS # 2103-64-2
Molecular Formula C₂₀H₁₂O₇
Molecular Weight 364.31
Purity ≥97%
Solubility >25 mg/ml DMSO
SMILES OC1=CC=C(C(C(C=CC=C5)=C5C(O4)=O)4C(C=CC(O)=C3O)=C3O2)C2=C1O
InChi InChI=1S/C20H12O7/c21-13-7-5-11-17(15(13)23)26-18-12(6-8-14(22)16(18)24)20(11)10-4-2-1-3-9(10)19(25)27-20/h1-8,21-24H
InChi Key PHLYOKFVXIVOJC-UHFFFAOYSA-N
PubChem CID 73685
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Gallein is an inhibitor of G protein βγ subunit-dependent signaling. Blocks PI 3-kinase and Rac1 activation in HL60 cells and chemotaxis in HL60 differentiated cells. It inhibits metastatic spread of tumor cells expressing OR51E2 and exposed to its odorant ligand.


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