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Galectin-3, mouse recombinant

A protein involved in cell growth and differentiation, cell cycle, and apoptosis.
Catalog #: P1045

In stock

SKU-Size Size Price Qty
P1045-10 10 μg
$105.00
P1045-50 50 μg
$495.00
More Sizes Get Quote

Product Details

Alternate Name CBP35, GAL3, GALBP, GALIG, LGALS2, MAC2.
Gene Symbol Lgals3
Gene ID 16854
Accession # Q8C253
Source E. coli
Appearance Liquid
Physical Form Description In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 50% glycerol,1mM DTT, 2mM EDTA
Molecular Weight 29.8 kDa
Purity by SDS-PAGE > 95%
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSMADSFSL NDALAGSGNP NPQGYPGAWG NQPGAGGYPG AAYPGAYPGQ APPGAYPGQA PPGAYPGQAP PSAYPGPTAPGAYPGPTAPG AYPGSTAPGA FPGQPGAPGA YPSAPGGYPA AGPYGVPAGP LTVPYDLPLP GGVMPRMLIT IMGTVKPNAN RIVLDFRRGN DVAFHFNPRFNENNRRVIVC NTKQDNNWGK EERQSAFPFE SGKP
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

LGALS3, also known as galectin 3, is a member of the family of animal lectins, which selectively binds betagalactosidemresidues. This protein is secreted from cells by ectocytosis, which is independent of the classical secretory pathway through the endoplasmic reticulum/Golgi network. LGALS3 has been associated with the inhibition of apoptosis and the progression of cancer. It is normally distributed in epithelia of many organs, in various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins. Recombinant mouse LGALS3 protein, used to Histag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.


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