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Galectin-3, human recombinant

A protein involved in cell growth and differentiation, cell cycle, and apoptosis.
Catalog #: 4684
SKU-Size Size Price Qty
4684-10 10 μg
$80.00
4684-50 50 μg
$190.00
4684-1000 1 mg
$1,450.00
More Sizes Get Quote

Product Details

Alternate Name IgE-binding protein, MAC2, L-29, CPB-35, 35 kDa lectin, Carbohydrate-binding protein 35, Galactose-specific lectin 3, Galactoside-binding protein, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen
Gene Symbol LEG3
Gene ID 3958
Accession # P17931
Source E. coli
Appearance Lyophilized protein
Physical Form Description Sterile filtered and lyophilized from 0.5X PBS, pH 7.2.
Molecular Weight 26.0 kDa
Purity by SDS-PAGE ≥98%
Endotoxin Level <0.1 ng/μg
Biological Activity Determined by its ability to chemoattract human blood monocytes. Chemotactic activity was observed at a concentration of 2.5 µg/ml with a peak response obtained at 250 µg/ml.
Reconstitution Instructions Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Lectins are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with β-galactoside moieties. Galactin-3 regulates a number of biological processes, including embryogenesis, inflammatory responses, cell progression and metastasis. Galectin-3 can function intraCellularly in controlling cell cycle and preventing T-cell apoptosis, and also extraCellularly, in activating various cells, including monocytes/macrophages, mast cells, neutrophils, and lymphocytes. Recombinant Galectin-3 is a globular 26.0 kDa protein containing 250 amino acid residues, but no disulfide bonds.


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