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Galantamine Hydrobromide

An inhibitor of acetylcholinesterase
Catalog #: B3094
SKU-Size Size Price Qty
B3094-10 10 mg
$60.00
B3094-50 50 mg
$235.00
More Sizes Get Quote

Product Details

Alternate Name Galanthamine hydrobromide; Reminyl; (1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-ol;hydrobromide; (4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol Hydrobromide
Appearance White crystalline solid
CAS # 1953-04-4
Molecular Formula C₁₇H₂₂BrNO₃
Molecular Weight 368.27
Purity ≥ 98%
Solubility ~7 mg/ml in water, ~7 mg/ml in DMSO (may need gentle warming)
SMILES CN1CCC23C=CC(CC2OC4=C(C=CC(=C34)C1)OC)O.Br
InChi InChI=1S/C17H21NO3.BrH/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17;/h3-6,12,14,19H,7-10H2,1-2H3;1H/t12-,14-,17-;/m0./s1
InChi Key QORVDGQLPPAFRS-XPSHAMGMSA-N
PubChem CID 121587
MDL Number MFCD00067672
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20 °C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

Galantamine is an alkaloid originally isolated from the bulbs and flowers of various Galanthus species. It inhibits acetylcholinesterase with an IC₅₀ of 800 nM. It is a potent allosteric potentiating ligand of human α₃β₄, α₄β₂ and α₆β₄ nicotinic receptors (nAChRs). It is used for the treatment of vascular dementia in Alzheimer’s disease.


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