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α-Galactosylceramide

A specific ligand for human and mouse natural killer T (NKT) cells
Catalog #: 2152
SKU-Size Size Price Qty
2152-250 250 µg
$175.00
2152-1000 1 mg
$445.00
More Sizes Get Quote

Product Details

Alternate Name alpha-Galactosylceramide; αGalCer; KRN7000; (2S,3S,4R)-1-O-(α-D-galactosyl)-N-hexacosanoyl-2-amino- 1,3,4-octadecanetriol
Appearance White to off-white solid
CAS # 158021-47-7
Molecular Formula C₅₀H₉₉NO₉
Molecular Weight 858.32
Purity ≥96% by NMR
Solubility For In vivo assay: Use 5.6% sucrose, 0.75% L-histidine and 0.5% Tween20 with heating at 60-80 ̊C. For In vitro assay: should be dissolved in DMSO at the concentration of 1 mg/ml with heating at 60-80 ̊C . The solution of 1mg/ml in DMSO can be diluted by P
SMILES CCCCCCCCCCCCCCCCCCCCCCCCCC(=O)NC(COC1C(C(C(C(O1)CO)O)O)O)C(C(CCCCCCCCCCCCCC)O)O
InChi InChI=1S/C50H99NO9/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-25-26-27-29-31-33-35-37-39-45(54)51-42(41-59-50-49(58)48(57)47(56)44(40-52)60-50)46(55)43(53)38-36-34-32-30-28-16-14-12-10-8-6-4-2/h42-44,46-50,52-53,55-58H,3-41H2,1-2H3,(H,51,54)/t42-,43+,44+,46-,47-,48-,49+,50-/m0/s1
InChi Key VQFKFAKEUMHBLV-BYSUZVQFSA-N
PubChem CID 2826713
MDL Number MFCD00939559
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

α-GalCer is a specific ligand for human and mouse natural killer T (NKT) cells; exhibits potent anti-tumor activity with murine in vivo experiments including subcutaneous implanted model and metastatic models in the liver and lung. KRN7000 has been reported to show various immunological effects in infectious diseases, autoimmune disease and graft verse host disease in mice.


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