GAAP Antibody

Polyclonal Antibody to detect GAAP in human, mouse and rat samples
Catalog #: 3524 | abID:

Product Details

Antibody Target GAAP
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide at N-terminal
Accession # P55061
Gene ID 7009
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 µg (0.5 mg/ml) of antibody in PBS, 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol, pH 7.2
Purification Affinity purified
Species Reactivity Human, mouse, rat
Application Western blot
Positive Control Western blot: Jurkat cell lysate, 3T3 cell lysate
Application & Usage Western blot: 1:200
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


The BI-1 (Bax inhibitor 1) family is evolutionarily conserved as integral membrane proteins containing multiple membrane-spanning domains that are predominantly localized to intracellular membranes. BI-1 family members share multiple motifs and transcriptional factors within the promoter and the coding regions. They represent regulators of cell death pathways and are highly conserved in evolution from plants to insects, amphibians, mammals and pox-viruses. GAAP (Golgi anti-apoptotic protein), also known as TMBIM4 (transmembrane Bax inhibitor motif containing 4), S1R, ZPRO or CGI-119, is a 238 amino acid multi-pass membrane protein that belongs to the BI-1 family. Ubiquitously expressed, GAAP inhibits apoptosis induced by intrinsic and extrinsic apoptotic stimuli.

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