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Funalenone

A MMP-1 inhibitor
Catalog #: B3225
$235.00

Product Details

Cat # +Size B3225-1
Size 1 mg
Alternate Name 3,4,7,9-Tetrahydroxy-6-methyl-1H-phenalen-1-one
Peptide Sequence N/A
Appearance Crystalline solid
CAS # 259728-61-5
Molecular Formula C₁₅H₁₂O₆
Molecular Weight 288.3
Purity ≥95%
Solubility DMSO
SMILES O=C1C(OC)=C(O)C2=C(O)C=C(C)C3=C2C1=C(O)C=C3O
InChi InChI=1S/C15H12O6/c1-5-3-6(16)10-12-9(5)7(17)4-8(18)11(12)14(20)15(21-2)13(10)19/h3-4,16-19H,1-2H3
InChi Key QAPJKCNKHLDDAK-UHFFFAOYSA-N
PubChem CID 312243941
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Funalenone, a phenalene compound isolated from mycelium of Aspergillus niger FO-5904, acts as an inhibitor of type I collagenase (MMP-1). Funalenone inhibits 50% of type I collagenase activity at a concentration of 170 µM but inhibits 18.3% and 38.7% against 72 kDa and 92 kDa type IV collagenase, respectively, at a concentration of 400 µM.


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