FTO, mouse recombinant

The gene responsible for mouse ‘fused toes’ mutation.
Catalog #: 7558 | abID:

Product Details

Cat # +Size 7558-10
Size 10 μg
Alternate Name Fat Mass and Obesity-associated Protein; FATSO.
Gene Symbol FTO
Gene ID 26383
Accession # Q8BGW1
Source E. coli
Appearance Liquid
Physical Form Description 0.5 mg/ml of 0.2 μm-filtered solution in 55 mM Tris-Cl, pH 8.2 containing 150 mM NaCl.
Molecular Weight ~55 kDa (SDS-PAGE). Mouse FTO (aa 2-502) is fused at the N-terminus to a His-tag.
Purity by SDS-PAGE ≥90%
Endotoxin Level <1 EU/μg by LAL method
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans


FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.

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